The story centers on chronic pain sufferer Claire (Aniston) as she struggles to come to terms, not only with the aftermath of the car accident that killed her son and left her partially disabled by chronic pain, but also with the suicide of a woman from her chronic pain support group, Nina (Kendrick). The film documents how Claire's pain and grief affect her behavior, her relationships with other people, and her ability to function from just after Nina's death until she reaches a breakthrough point in her own path.
This is a dark, depressing film about the world of some chronic pain sufferers. It comments on opioids as well. It is well done and worth seeing.